Wireless technology had a remarkable success over the years but it still faces challenges like multiple interference and spectrum limitations. Therefore, Cellular communication evolution leads to create a new interface called Long term Evolution. It is a 3rd Generation Partnership Project within the Universal Mobile Telecommunication System. In order to improve the spectrum limitations, multiple interference new modulation techniques, enhanced antenna configurations and standard coding schemes are introduced to improve the overall performance of the system i.e., increased bandwidth within the specified frequency band to individual operators, reduced latencies as technical aspects and Push-To-Talk, machine-type communications being service oriented. In this paper, the main objective is to analyze the Long Term Evolution physical layer in Simulink environment by observing the bit error rate with different modulation techniques, channel models and antenna configurations.