The recent mobile networks provide large data access using long-term evolution networks. Long-term evolution networks are a third-generation partnership project standard that provides different speed limits for uplink and downlink. The different network operators have different bandwidth requirements to provide different services. Long-term evolution improves the efficiency of the network. The analysis of long-term evolution is performed using different signal processing algorithms that require a realistic, flexible, and standard compliant simulation environment. This study emphasizes to measure the performance of long-term evolution downlink and uplink physical layer based on Release 11, 12, and 13. The analysis of orthogonal frequency division multiple access for downlink and single-carrier frequency division multiplexing access for uplink using different modulation schemes like quadrature amplitude modulation (4, 16, 64) and different antenna configurations in long-term evolution physical layer is analyzed using hardware cosimulation platform.